Mixtral 8x22B Instruct APIOPEN WEIGHTS66K context
Mistral's official instruct fine-tuned version of [Mixtral 8x22B](/models/mistralai/mixtral-8x22b).
Pricing & specs mirror our live pricing as of July 2026 (pay-as-you-go).
What is Mixtral 8x22B Instruct?
Mistral's official instruct fine-tuned version of [Mixtral 8x22B](/models/mistralai/mixtral-8x22b). It uses 39B active parameters out of 141B, offering unparalleled cost efficiency for its size. Its strengths include: - strong math, coding,...
Mixtral 8x22B Instruct on the release timeline
Mixtral 8x22B Instruct pricing
Pay-as-you-go on DataLLM Lab — these are our live list prices (identical to the pricing page):
| Model | Input / 1M | Output / 1M | Cache read | Cache write | Context |
|---|---|---|---|---|---|
| Mixtral 8x22B Instruct | $2.00 | $6.00 | $0.20 | — | 66K |
On output price, Mixtral 8x22B Instruct is cheaper than 25% of the 309 models in the catalog.
What Mixtral 8x22B Instruct costs per month
| Workload | Tokens in / out (monthly) | Est. cost |
|---|---|---|
| Support chatbot | 40M / 12M | $152 |
| RAG / knowledge base | 200M / 20M | $520 |
| Coding agent | 80M / 25M | $310 |
| Batch extraction | 150M / 8M | $348 |
| Content generation | 20M / 40M | $280 |
Estimate your own monthly cost
Cost = input price × input volume + output price × output volume. The same five workloads run on every model page, so any two compare directly.
Mixtral 8x22B Instruct vs alternatives
| Model | Input / 1M | Output / 1M | Context | Our test |
|---|---|---|---|---|
| Mixtral 8x22B Instruct | $2.00 | $6.00 | 66K | — |
| Mistral Large | $2.00 | $6.00 | 128K | — |
| Mistral Large 2407 | $2.00 | $6.00 | 131K | — |
| Mistral Large | $2.00 | $6.00 | 128K | — |
| Palmyra X5 | $0.60 | $6.00 | 1M | — |
| Qwen3.6 Max Preview | $1.04 | $6.24 | 262K | — |
When not to use Mixtral 8x22B Instruct
- It is premium-priced (output cheaper than only 25% of the catalog) — for routine work a cheaper model likely does the job.
- It is served by a single provider, so there is less failover headroom during an outage.
Specs
| Model ID | mistralai/mixtral-8x22b-instruct |
| Modality | text+file->text (input: text, file) |
| Context window | 65,536 tokens |
| Tool / function calling | ✅ Yes |
| Structured output (JSON) | ✅ Yes |
| Released | 2024-04-17 |
| Knowledge cutoff | 2024-01-31 |
| Open weights | ✅ mistralai/Mixtral-8x22B-Instruct-v0.1 · 62.3K downloads / 752 likes (30d) |
How to call Mixtral 8x22B Instruct
from openai import OpenAI
client = OpenAI(base_url="https://api.datallmlab.com/v1", api_key="YOUR_DATALLM_LAB_KEY")
resp = client.chat.completions.create(
model="mistralai/mixtral-8x22b-instruct",
messages=[{"role": "user", "content": "Hello"}],
# supports tools=[...] and tool_choice
)
print(resp.choices[0].message.content)curl https://api.datallmlab.com/v1/chat/completions \
-H "Authorization: Bearer YOUR_KEY" \
-H "Content-Type: application/json" \
-d '{"model":"mistralai/mixtral-8x22b-instruct","messages":[{"role":"user","content":"Hello"}]}'import OpenAI from "openai";
const client = new OpenAI({ baseURL: "https://api.datallmlab.com/v1", apiKey: process.env.DATALLM_KEY });
const r = await client.chat.completions.create({
model: "mistralai/mixtral-8x22b-instruct",
messages: [{ role: "user", content: "Hello" }],
});
console.log(r.choices[0].message.content);The same key routes Mixtral 8x22B Instruct and 300+ other models — switch models by changing one string. How OpenAI-compatible APIs work.
Prompting tips for Mixtral 8x22B Instruct
- Be explicit and show the shape of the answer. Spell out format, tone and constraints up front, and include one short example of the output you want — Mixtral 8x22B Instruct follows concrete instructions better than abstract ones.
- Give it real tools. Pass a
tools=[...]schema instead of asking it to "pretend" — let Mixtral 8x22B Instruct emit tool calls, execute them, and feed results back for the next turn. - Constrain JSON with a schema. Use
response_format/ structured outputs rather than "reply in JSON" to get valid, parseable objects every time. - It's premium — spend where it counts. Route easy calls to a cheaper model and reserve Mixtral 8x22B Instruct for the hard reasoning; trim system prompts and few-shot examples that don't move the result.
Tips are derived from Mixtral 8x22B Instruct's actual capabilities — context window, tool & JSON support, modality and price tier — not generic advice.
Open-source tools for Mixtral 8x22B Instruct
Popular open-source projects for running and building with Mixtral 8x22B Instruct — star counts pulled from GitHub (July 2026).
Listed by GitHub stars; inclusion is by ecosystem relevance (inference engines, agent frameworks and SDKs), not affiliation. Stars change — see each repo for current numbers.
Migrating to Mixtral 8x22B Instruct
Coming from OpenAI or another gateway? On an OpenAI-compatible setup the only changes are base_url → https://api.datallmlab.com/v1 and model → mistralai/mixtral-8x22b-instruct. Messages, streaming, tool calls and the rest of your code stay the same. Routing & failover guide.
Self-host or use the API?
Mixtral 8x22B Instruct ships open weights (mistralai/Mixtral-8x22B-Instruct-v0.1, ~62.3K downloads and 752 likes in the last 30 days), so you can run it yourself. Most teams still use the API: no GPU to provision or keep warm, no inference ops, and instant access across 1 providers with automatic failover. Self-host when data residency or fixed per-token economics matter most.
Rate limits & reliability
Rate limits here are the DataLLM Lab gateway's, not the upstream vendor's. On 429 (rate limited) or 503 (provider busy), retry with exponential backoff. See the error-code guide and failover setup.
Related reading
Call Mixtral 8x22B Instruct with one key
300+ models behind one OpenAI-compatible endpoint — better prices, better uptime, no subscriptions.
Get an API keyCompare pricingFrequently asked questions
What is Mixtral 8x22B Instruct?
Mistral's official instruct fine-tuned version of [Mixtral 8x22B](/models/mistralai/mixtral-8x22b). It accepts text, file input with a 66K-token context window and was released on 2024-04-17. On DataLLM Lab it is callable through one OpenAI-compatible endpoint.
How much does Mixtral 8x22B Instruct cost?
On DataLLM Lab it is $2.00 per 1M input tokens and $6.00 per 1M output tokens, with cached input at $0.20/1M — cheaper than about 25% of the 309-model catalog on output price. Pay-as-you-go, no subscription.
What is the context window of Mixtral 8x22B Instruct?
66K tokens.
Is Mixtral 8x22B Instruct open source?
Yes — open weights are published on Hugging Face (mistralai/Mixtral-8x22B-Instruct-v0.1), with about 62.3K downloads and 752 likes in the last 30 days. You can self-host it or call it via DataLLM Lab.
How do I call the Mixtral 8x22B Instruct API?
Point any OpenAI SDK at https://api.datallmlab.com/v1 and set model to "mistralai/mixtral-8x22b-instruct". One DataLLM Lab key routes this model and 300+ others; no code changes beyond the base URL and model string.
What are good alternatives to Mixtral 8x22B Instruct?
Close options by price and capability include Mistral Large, Mistral Large 2407, Mistral Large — all callable with the same DataLLM Lab key.