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Models / Mistral / Mixtral 8x22B Instruct

Mixtral 8x22B Instruct APIOPEN WEIGHTS66K context

by Mistral · text+file->text · released 2024-04-17

Mistral's official instruct fine-tuned version of [Mixtral 8x22B](/models/mistralai/mixtral-8x22b).

Get an API key Try in Chat https://api.datallmlab.com/v1
Input / 1M
$2.00
Output / 1M
$6.00
Context
66K
Providers
1
HF downloads · 30d
62.3K
Cheaper than
25% of catalog

Pricing & specs mirror our live pricing as of July 2026 (pay-as-you-go).

What is Mixtral 8x22B Instruct?

Mistral's official instruct fine-tuned version of [Mixtral 8x22B](/models/mistralai/mixtral-8x22b). It uses 39B active parameters out of 141B, offering unparalleled cost efficiency for its size. Its strengths include: - strong math, coding,...

Mixtral 8x22B Instruct on the release timeline

$0.08$0.77$7.50Mixtral 8x22B Instruct · $6.002024-042025-102026-04
Each point is a Mistral model, placed at its launch date with its current output price (log scale, $/1M). Bubble size ∝ context window; Mixtral 8x22B Instruct is highlighted. Source: provider catalog, verified July 2026.

Mixtral 8x22B Instruct pricing

Pay-as-you-go on DataLLM Lab — these are our live list prices (identical to the pricing page):

ModelInput / 1MOutput / 1MCache readCache writeContext
Mixtral 8x22B Instruct$2.00$6.00$0.2066K

On output price, Mixtral 8x22B Instruct is cheaper than 25% of the 309 models in the catalog.

What Mixtral 8x22B Instruct costs per month

WorkloadTokens in / out (monthly)Est. cost
Support chatbot40M / 12M$152
RAG / knowledge base200M / 20M$520
Coding agent80M / 25M$310
Batch extraction150M / 8M$348
Content generation20M / 40M$280

Estimate your own monthly cost

= input × $2.00 + output × $6.00 per 1M · pay-as-you-go, computed in your browser.

Cost = input price × input volume + output price × output volume. The same five workloads run on every model page, so any two compare directly.

Mixtral 8x22B Instruct vs alternatives

Pick Mixtral 8x22B Instruct when you want open weights you can also self-host. If price is the only priority, it is already the cheapest here.
ModelInput / 1MOutput / 1MContextOur test
Mixtral 8x22B Instruct$2.00$6.0066K
Mistral Large$2.00$6.00128K
Mistral Large 2407$2.00$6.00131K
Mistral Large$2.00$6.00128K
Palmyra X5$0.60$6.001M
Qwen3.6 Max Preview$1.04$6.24262K

When not to use Mixtral 8x22B Instruct

Specs

Model IDmistralai/mixtral-8x22b-instruct
Modalitytext+file->text (input: text, file)
Context window65,536 tokens
Tool / function calling✅ Yes
Structured output (JSON)✅ Yes
Released2024-04-17
Knowledge cutoff2024-01-31
Open weightsmistralai/Mixtral-8x22B-Instruct-v0.1 · 62.3K downloads / 752 likes (30d)

How to call Mixtral 8x22B Instruct

from openai import OpenAI
client = OpenAI(base_url="https://api.datallmlab.com/v1", api_key="YOUR_DATALLM_LAB_KEY")
resp = client.chat.completions.create(
    model="mistralai/mixtral-8x22b-instruct",
    messages=[{"role": "user", "content": "Hello"}],
    # supports tools=[...] and tool_choice
)
print(resp.choices[0].message.content)
curl https://api.datallmlab.com/v1/chat/completions \
  -H "Authorization: Bearer YOUR_KEY" \
  -H "Content-Type: application/json" \
  -d '{"model":"mistralai/mixtral-8x22b-instruct","messages":[{"role":"user","content":"Hello"}]}'
import OpenAI from "openai";
const client = new OpenAI({ baseURL: "https://api.datallmlab.com/v1", apiKey: process.env.DATALLM_KEY });
const r = await client.chat.completions.create({
  model: "mistralai/mixtral-8x22b-instruct",
  messages: [{ role: "user", content: "Hello" }],
});
console.log(r.choices[0].message.content);

The same key routes Mixtral 8x22B Instruct and 300+ other models — switch models by changing one string. How OpenAI-compatible APIs work.

Prompting tips for Mixtral 8x22B Instruct

Tips are derived from Mixtral 8x22B Instruct's actual capabilities — context window, tool & JSON support, modality and price tier — not generic advice.

Open-source tools for Mixtral 8x22B Instruct

Popular open-source projects for running and building with Mixtral 8x22B Instruct — star counts pulled from GitHub (July 2026).

ollama/ollama★ 175.3K
Get up and running with Kimi-K2.6, GLM-5.1, MiniMax, DeepSeek, gpt-oss, Qwen, Gemma and other models.
Go
langgenius/dify★ 147.5K
Production-ready platform for agentic workflow development.
TypeScript
open-webui/open-webui★ 144.0K
User-friendly AI Interface (Supports Ollama, OpenAI API, ...)
Python
langchain-ai/langchain★ 140.8K
The agent engineering platform.
Python
ggml-org/llama.cpp★ 119.1K
LLM inference in C/C++
C++
vllm-project/vllm★ 85.2K
A high-throughput and memory-efficient inference and serving engine for LLMs
Python

Listed by GitHub stars; inclusion is by ecosystem relevance (inference engines, agent frameworks and SDKs), not affiliation. Stars change — see each repo for current numbers.

Migrating to Mixtral 8x22B Instruct

Coming from OpenAI or another gateway? On an OpenAI-compatible setup the only changes are base_url → https://api.datallmlab.com/v1 and model → mistralai/mixtral-8x22b-instruct. Messages, streaming, tool calls and the rest of your code stay the same. Routing & failover guide.

Self-host or use the API?

Mixtral 8x22B Instruct ships open weights (mistralai/Mixtral-8x22B-Instruct-v0.1, ~62.3K downloads and 752 likes in the last 30 days), so you can run it yourself. Most teams still use the API: no GPU to provision or keep warm, no inference ops, and instant access across 1 providers with automatic failover. Self-host when data residency or fixed per-token economics matter most.

Rate limits & reliability

Rate limits here are the DataLLM Lab gateway's, not the upstream vendor's. On 429 (rate limited) or 503 (provider busy), retry with exponential backoff. See the error-code guide and failover setup.

Related reading

Best Open Source LLMs
DataLLM Lab Blog
How OpenAI-Compatible APIs Work
DataLLM Lab Blog
We Benchmarked LLM Coding Cost & Quality
DataLLM Lab Blog

Call Mixtral 8x22B Instruct with one key

300+ models behind one OpenAI-compatible endpoint — better prices, better uptime, no subscriptions.

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Frequently asked questions

What is Mixtral 8x22B Instruct?

Mistral's official instruct fine-tuned version of [Mixtral 8x22B](/models/mistralai/mixtral-8x22b). It accepts text, file input with a 66K-token context window and was released on 2024-04-17. On DataLLM Lab it is callable through one OpenAI-compatible endpoint.

How much does Mixtral 8x22B Instruct cost?

On DataLLM Lab it is $2.00 per 1M input tokens and $6.00 per 1M output tokens, with cached input at $0.20/1M — cheaper than about 25% of the 309-model catalog on output price. Pay-as-you-go, no subscription.

What is the context window of Mixtral 8x22B Instruct?

66K tokens.

Is Mixtral 8x22B Instruct open source?

Yes — open weights are published on Hugging Face (mistralai/Mixtral-8x22B-Instruct-v0.1), with about 62.3K downloads and 752 likes in the last 30 days. You can self-host it or call it via DataLLM Lab.

How do I call the Mixtral 8x22B Instruct API?

Point any OpenAI SDK at https://api.datallmlab.com/v1 and set model to "mistralai/mixtral-8x22b-instruct". One DataLLM Lab key routes this model and 300+ others; no code changes beyond the base URL and model string.

What are good alternatives to Mixtral 8x22B Instruct?

Close options by price and capability include Mistral Large, Mistral Large 2407, Mistral Large — all callable with the same DataLLM Lab key.